New Delhi, India – 110 016

Zoladex (Goserelin Acetate) Injection

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Generic brands for Goserelin Acetate Injection Available in India

Brand Name Zoladex
Generic Name Goserelin Acetate
Strength 3.5mg, 10.8mg
Manufacturer Astrazeneca Pharma India

 

Original price was: ₹9,754.00.Current price is: ₹7,482.00.

Description

Description

This page contains brief details about the drug goserelin acetate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Goserelin Acetate is a gonadotropin-releasing hormone agonist. Goserelin Acetate 3.6mg implant was approved in 1989 whereas Goserelin Acetate 10.8mg was approved in 1996.

ZOLADEX 3.6MG INJ. 1X1 7482 9754

Mechanism of Action of Goserelin Acetate

Goserelin Acetate is a synthetic analogue of gonadotropin releasing hormone that binds to the gonadotropin receptors of pituitary gland. It lowers the androgen and testosterone levels in men and oestrogen levels in women. It is prescribed in combination with androgen antagonist like flutamide to prevent the initial flare up of tumor.

Uses of Goserelin Acetate

Goserelin Acetate Injection is an anticancer medication indicated for the palliative treatment of Advanced prostate cancer and breast cancer. It is also indicated as an endometrial thinning agent in uterine bleeding and for the management of endometriosis.

Goserelin Acetate Dosage available

Goserelin Acetate is available as a prefilled syringe indicated as an implant in the doses 3.6mg, and 10.8mg.  It is administered through subcutaneous route.

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References

1. TerSera Therapeutics LLC., [Revised on Dec 2020] [Accessed on 28th Sep 2022], https://documents.tersera.com/zoladex-us/3.6mg_MagnumPI.pdf

2. TerSera Therapeutics LLC., [Revised on Dec 2020] [Accessed on 28th Sep 2022], https://documents.tersera.com/zoladex-us/10.8mg_MagnumPI.pdf

3. KD Tripathi, Essentials of Medical Pharmacology, Anterior Pituitary Hormones, 8th Edition, 2019, 257-266.

4. Claudine Isaacs, Anton Wellstein, and Anna T. Riegel, Hormones and Related Agents in the Therapy of Cancer, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1237-1247.

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