New Delhi, India – 110 016

Zebical (Bicalutamide) available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Zebical (Bicalutamide) Tablet

Generic brands for Bicalutamide Injection  Available in India

Brand Name Zebical
Generic Name Bicalutamide
Strength 50mg
Manufacturer Zee Laboratories Ltd

Description

Description

This page contains brief details about the drug bicalutamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Bicalutamide is an oral non-steroidal anti-androgenic drug used to treat stage 2 metastatic prostate cancer. It was approved by the FDA on 19 December 2008.

Mechanism of Action of Bicalutamide

Antiandrogens counter male hormonal action by interfering with the synthesis of androgens or by blocking their receptors. Bicalutamide, anti-androgen, competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin, which stimulate the growth of normal and malignant prostatic tissues. Thereby reducing the growth and spread of cancer.

Uses of Bicalutamide

Bicalutamide is in a class of medications called nonsteroidal antiandrogens. It works by blocking the effect of androgen (a male hormone) to stop the growth and spread of cancer cells in the prostate gland (located just below the bladder in men). It is indicated for use in combination therapy with a luteinizing hormone-releasing hormone (LHRH) agonist to treat Stage D2 metastatic carcinoma of the prostate.

Bicalutamide Dosage available

Bicalutamide is a prescribed drug available as a 50 mg tablet. The recommended dose in combination with a luteinizing hormone-releasing hormone (LHRH) analog is one 50 mg tablet once daily (morning or evening) to treat stage D2 metastatic prostate cancer. Your healthcare physician will prescribe the medicine based on the condition.

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References

  1. HIGHLIGHTS OF PRESCRIBING INFORMATION. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020498s028lbl.pdf (Accessed on 21 December 2022)
  2. Casodex (bicalutamide) dosing, indications, interactions, adverse effects, and more. reference.medscape.com. Accessed December 22, 2022. https://reference.medscape.com/drug/casodex-bicalutamide-342210#5
  3. Micromedex products: (Last Modified: November 22, 2022) Available at: https://www.micromedexsolutions.com/micromedex2/librarian/PFDefaultActionId/evidencexpert.DoIntegratedSearch?navitem=topHome&isToolPage=true#  (Accessed: December 22, 2022). 
  4. Bicalutamide. go.drugbank.com. Published December 20, 2022. (Accessed December 22, 2022). https://go.drugbank.com/drugs/DB01128
  5. Liu C, Armstrong CM, Lou W, Lombard AP, Cucchiara V, Gu X, Yang JC, Nadiminty N, Pan CX, Evans CP, Gao AC. Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer. Mol Cancer Ther. 2017 Aug;16(8):1521-1530. doi: 10.1158/1535-7163.MCT-16-0912. Epub 2017 May 12. PMID: 28500234; PMCID: PMC5544572.
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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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