Description
Description
This page contains brief details about the drug sofosbuvir,velpatasvir, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Sofosbuvir, Velpatasvir is an antiviral medication that was approved for its medical use on 28th June 2016.
Mechanism of Action of Sofosbuvir + Velpatasvir
Sofosbuvir, Velpatasvir tablet is a Hepatitis C virus nucleotide analog belonging to the class of NS5B polymerase inhibitor. This combination stops RNA synthesis in the Hepatitis C virus and acts as a chain terminator by stopping viral replication.
Uses of Sofosbuvir + Velpatasvir
Sofosbuvir, Velpatasvir is a fixed-dose combination consisting of 400 mg of sofosbuvir and 100mg of velpatasvir. It is indicated to treat adult and pediatric patients above 3 years of age with chronic Hepatitis C virus infection with or without liver cirrhosis.
Sofosbuvir + Velpatasvir Dosage available
For patients with compensated and decompensated cirrhosis, the recommended duration of treatment is 12 weeks. However, for decompensated cirrhosis, this treatment is prescribed along with Ribavirin. The recommended dosage for adults is one tablet per day with or without food. The ideal dose for pediatric patients is calculated based on body weight. For children below 6 years of age, it is advisable to administer Sofosbuvir, Velpatasvir tablets with food.
