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Trulicity (Dulaglutide) Injection

Generic brands for Dulaglutide Injection Available in India

Brand Name Trulicity
Generic Name Dulaglutide
Strength 0.75mg, 1.5mg
Manufacturer Eli Lilly And Company Ind

Description

Description

This page contains brief details about the drug dulaglutide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Dulaglutide contains active components as dulaglutide. It is a medication that is used to treat type 2 diabetes. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Dulaglutide works by mimicking the action of a hormone called glucagon-like peptide-1 (GLP-1) in the body. It is typically used in combination with other diabetes medications, such as metformin or sulfonylureas, when diet and exercise alone are not sufficient to control blood sugar levels. This medication improves glycemic control and helps prevent hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). Many people with type 2 diabetes struggle with weight management. This medication has been shown to promote weight loss or maintenance in some individuals. This can benefit overall health and contribute to better diabetes management. It received FDA approval on September 17, 2014, for treating type 2 diabetes.

Mechanism of Action of Dulaglutide

Dulaglutide, a GLP-1 receptor agonist, improves glycemic control in individuals with type 2 diabetes by stimulating insulin secretion, suppressing glucagon release (a hormone that prevents excessive glucose production by the liver.), and slowing gastric emptying. These actions work together to lower blood sugar levels, promote weight loss or weight maintenance, and reduce appetite. By addressing multiple aspects of diabetes management, this medication offers a comprehensive therapeutic effect for individuals with type 2 diabetes.

Uses of Dulaglutide

Dulaglutide is a medication approved for the management of type 2 diabetes.

Dulaglutide Dosage available

Dulaglutide is typically administered by a healthcare professional once in a week. It is usually given as an injection. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.

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References

  1. Eli Lilly and Company Limited, Electronic medicines compendium (EMC), [Revised on 25th May 2023], [Accessed on 31st May 2023], https://www.medicines.org.uk/emc/files/pil.3634.pdf
  2. Eli Lilly and Company, US Food and Drug Administration, [Revised on January 2017] [Accessed on 1st June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/125469s007s008lbl.pdf 
  3. KD Tripathi, Essentials of Medical Pharmacology, 2018, 8th Edition, 1002-1008
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