New Delhi, India – 110 016

Tecfidera (Dimethyl Fumarate) Capsule

Generic brands for Dimethyl Fumarate Tablets Available in India

Brand Name Tecfidera
Generic Name Dimethyl Fumarate
Strength 120mg
Manufacturer EISAI PHARMACEUTICALS INDIA PVT LTD

 

 

Description

Description

Tecfidera 120mg Capsule is an immunosuppressant medication containing the active ingredient Dimethyl Fumarate. This medication primarily treats relapsing forms of multiple sclerosis (MS), including relapsing-remitting and active secondary progressive multiple sclerosis. It helps reduce the frequency of relapses and slows the progression of the disease

This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Before initiating the treatment with Tecfidera 120mg Capsule, your doctor will conduct essential tests to assess white blood cell counts, liver and kidney function. Periodic monitoring will continue throughout treatment to ensure your well-being. If certain conditions apply to you, such as severe kidney or liver disease, stomach or bowel issues, or a serious infection like herpes zoster (shingles). In that case, you should discuss these with your physician before taking this drug

Tecfidera 120mg Capsule can be used in children and adults aged 13 years and above. Do not use this drug if you are suspected to have or have confirmed progressive multifocal leukoencephalopathy (PML), a rare brain infection. Your doctor shall prescribe this medicine during pregnancy only if necessary. If you are pregnant, suspecting, or planning for the pregnancy, report to your doctor before starting the treatment. It is unknown if this medicine passes into the breast milk. Please consult your doctor before breastfeeding.

Date of Approval

Adverse events reported during the study were flushing and gastrointestinal events decreased lymphocyte counts and elevated liver enzymes levels. On March 27, 2013, U.S. Food and Drug Administration approved dimethyl fumarate capsules to treat adults with relapsing forms of multiple sclerosis.

Mechanism of Action of Dimethyl Fumarate

Dimethyl fumarate (DMF) is an oral medication used to treat relapsing-remitting multiple sclerosis (RRMS).

Uses of Dimethyl Fumarate

Treat relapsing-remitting multiple sclerosis (MS)

Dimethyl Fumarate Dosage available

Take the Tecfidera 120mg Capsule as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.

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References

  1. Biogen Netherlands BV; Electronic Medicines Compendium; [Revised on May 2022], [Accessed on 31 August 2023], https://www.medicines.org.uk/emc/files/pil.5256.pdf
  2. Biogen; US Food And Drug Administration; [Revised on March 2013] [Accessed on 31 August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204063lbl.pdf
  3. HA Blair; Dimethyl fumarate: A Review in relapsing, remitting MS; [Revised on 2019] [Accessed on 31 August 2023], https://pubmed.ncbi.nlm.nih.gov/31784875/
  4. Jineane V Venci et al; Dimethyl fumarate (Dimethyl fumarate Capsule): A new oral agent for multiple sclerosis; [Revised on 2013] [Accessed on 31 August 2023], https://pubmed.ncbi.nlm.nih.gov/24259625/
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