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Sorafenat (Sorafenib) Tablet

Generic brands for Sorafenib Tablet Available in India

Brand Name Sorafenat
Generic Name Sorafenib
Strength 200mg
Manufacturer Natco Pharma Ltd

 

Description

Description

This page contains brief details about the drug sorafenib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Sorafenib is an antiangiogenic agent which was approved for its medical use on 20th December 2005.

Mechanism of Action of Sorafenib

Sorafenib acts as targeted drug therapy in cancer treatment. It is an anticancer medication that belongs to the category of tyrosine kinase inhibitors. It interferes with the growth of blood vessels inside the cancer cells and also acts against protein called receptor tyrosine kinases to interrupt cell signalling, ultimately stopping the growth and spread of cancer cells.

Uses of Sorafenib

Sorafenib has been developed to treat locally advanced and metastatic kidney cancer (renal cell carcinoma), thyroid cancer (progressive differentiated thyroid carcinoma) and liver cancer (unresectable hepatocellular carcinoma) after disease progression and inadequate response to other anticancer therapies.

Sorafenib Dosage available

Sorafenib is available in the form of film-coated tablets in the dose 200mg. The usual recommended adult dose is 800mg of Sorafenib a day. Take this tablet at the same time each day after a low-fat meal.

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News/Updates

References

  1. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
  2. Bayer Inc., [Revised on 27th Sep 2022] [Accessed on 8th Oct 2022], https://www.bayer.com/sites/default/files/2020-11/nexavar-pm-en.pdf
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