New Delhi, India – 110 016

Rolimus (Everolimus) Tablet

Generic brands for Everolimus Injection  Available in India

Brand Name Rolimus
Generic Name Everolimus
Strength 10mg
Manufacturer Cipla Ltd

 

Description

Description

This page contains brief details about the drug everolimus, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Everolimus is an immunosuppressant that was approved for its medical use on 30th March 2009.

Mechanism of Action of Everolimus

It contains the active ingredient everolimus, which inhibits the activity of a protein called mammalian target of rapamycin (mTOR), which regulates cell growth. This drug can slow the growth of abnormal cancer cells by blocking the mTOR protein. Everolimus helps to reduce the size of tumours and improve outcomes in patients.

Uses of Everolimus

Everolimus has been developed to treat advanced hormone receptor-positive breast cancer, pancreatic cancer (pancreatic neuroendocrine tumour), and neuroendocrine tumour of the stomach, lung, and intestine that cannot be treated with surgery.

Everolimus Dosage available

Take the Everolimus Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

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References

  1. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on June 2022] [ Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.6658.pdf
  2. Jan Hasskarl; Everolimus; Recent Results in Cancer Research; Published on 2018; Accessed on 18/03/2023; https://pubmed.ncbi.nlm.nih.gov/30069763/
  3. Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [ Revised on July 2012] [ Accessed on 18th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted therapy: tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1743.
  5. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878 – 882.
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