New Delhi, India – 110 016

Prugonist (Prucalopride) Tablet

Generic brands for Prucalopride Tablet Available in India

Brand Name Prugonist
Generic Name Prucalopride
Strength 1mg, 2mg
Manufacturer Mylan Pharmaceuticals Pvt Ltd

Description

Description

This page contains brief details about the drug prucalopride, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Prucalopride is a stimulant purgative drug developed by the U.S. Food And Drug Administration and initially approved in 2018 for treating chronic idiopathic constipation (CIC).

Mechanism of Action of Prucalopride

Prucalopride works by targeting specific serotonin receptors in the digestive system, which helps to stimulate bowel movements and improve the motility of the intestines. By enhancing intestinal contractions, this drug facilitates the movement of stool through the digestive tract, thereby relieving constipation.

Uses of Prucalopride

Prucalopride is used to treat chronic idiopathic constipation (CIC) in adults. Chronic idiopathic constipation is a medical condition caused by infrequent bowel movements and difficulty passing stool, which persists over an extended period without an identifiable underlying cause.

Prucalopride Dosage available

Take the Prucalopride as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

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News/Updates

References

  1. Dexcel®-Pharma Ltd., Electronic Medicines Compendium (EMC), [Revised on March 2023] [Accessed on 25th August 2023], https://www.medicines.org.uk/emc/files/pil.12622.pdf
  2. Shire US Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 25th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210166s000lbl.pdf
  3. I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.
  4. KD Tripathi, Drugs for Constipation and Diarrhoea, Essentials of Medical Pharmacology, 8th Edition, 2019, 721-738.
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