New Delhi, India – 110 016

Piciclib (Palbociclib) available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Piciclib (Palbociclib) Capsule

Generic brands for Palbociclib Capsule Available in India

Brand Name Piciclib
Generic Name Palbociclib
Strength 75mg, 100mg, 125mg
Manufacturer Cipla Ltd

Description

Description

This page contains brief details about the drug palbociclib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Palbociclib is an anticancer medication that was developed by Pfizer for treating breast cancer in postmenopausal women who tested positive for hormone receptors. It was initially approved in 2015 and later approved for treating metastatic breast cancer. Recently this medication has received a nod for its use in treating male breast cancer.

Mechanism of Action of Palbociclib

Palbociclib capsule produces its action by blocking the signal pathways of cyclin-dependent kinase 4 and 6 kinase enzymes involved in cancer cell proliferation. This medication inhibits cell division by attacking the cell division at the G phase to the S phase of the cell cycle.

Uses of Palbociclib

Palbociclib is used in the treatment of hormone-positive breast cancer. It is usually administered in combination with other hormonal therapy agents. Palbociclib is effective in treating breast cancer that has spread to other organs.

Palbociclib Dosage available

Palbociclib is intended for oral use only. It is often given along with other hormonal therapy agents. It must be consumed with meals and do not open/break the capsule. Palbociclib capsule is available in three different strengths 75mg capsule, 100 mg, and 125 mg capsules.

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News/Updates

References

  1. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
  2. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  3. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
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Frequently Asked Questions

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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