New Delhi, India – 110 016

Olabir (Olaparib) Tablet

Generic brands for Olaparib Tablet Available in India

Brand Name Olabir
Generic Name Olaparib
Strength 100mg, 150mg
Manufacturer Aprazer Healthcare Pvt Ltd

Description

Description

This page contains brief details about the drug olaparib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Olaparib is an anticancer medicine referred to as the Poly Adenosine Diphosphate-Ribose Polymerase (PARP) inhibitor. It was approved for its medical use on 19th December 2014.

Mechanism of Action of Olaparib

Olaparib Tablet is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a PARP inhibitor. PARP enzymes facilitate multiple DNA repair pathways and these repair mechanisms lead to the development of cancer cells. These enzymes specifically target cells with mutations in BRCA genes. Olaparib works by inhibiting PARP enzymes blocks repair of single stranded DNA, and ultimately hinders the growth and development of cancer cells. Olaparib is prescribed alone or in combination with other anticancer drugs like bevacizumab.

Uses of Olaparib

Olaparib Tablet has been developed as a maintenance therapy to treat adult patients with cancer in the ovaries, fallopian tube, peritoneum, pancreas, prostate due to BRCA mutation and have completely or partially responded to platinum-based chemotherapy.

Olaparib Dosage available

The recommended dose of Olaparib Tablet is 300mg twice a day with or without food. Olaparib Tablet is available in the doses of 100mg and 150mg and the strength varies according to the patient’s health condition. In patients with kidney impairment, the recommended dose is 200mg twice a day.

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News/Updates

References

  1. Sebastiaan C. Goulooze et al, Olaparib, Br J Clin Pharmaco, 81:1, 171-173, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693566/pdf/BCP-81-171.pdf
  2. AstraZeneca, US Food & Drug Administration, [Revised on Aug 2022] [Accessed on 9th Sep 2022], https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/00997c3f-5912-486f-a7db-930b4639cd51/00997c3f-5912-486f-a7db-930b4639cd51_viewable_rendition__v.pdf

Frequently Asked Questions

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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