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Lucaparib (Rucaparib) Tablet

Generic brands for Rucaparib Tablet Available in India

Brand Name Lucaparib
Generic Name Rucaparib
Strength 200mg, 300mg
Manufacturer Lupin Ltd

Description

Description

This page contains brief details about the drug rucaparib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Rucaparib is an anticancer drug that belongs to the class of medications called PARP (poly ADP-ribose polymerase) inhibitors. FDA approved this medicine on December 19, 2016, to treat certain types of cancers.

Mechanism of Action of Rucaparib

Rucaparib is an inhibitor of poly Adenosine diphosphate-ribose polymerase enzymes, including PARP-1, PARP-2, and PARP-3, which play a role in DNA repair. It blocks an enzyme that repairs damaged DNA in the cancer cells, resulting in their death.

Uses of Rucaparib

Rucaparib is an orally available prescription drug. It is used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube (a tube that transports eggs released by the ovaries to the uterus), and primary peritoneal (layer of tissue that lines the abdomen) cancer that has reoccurred in adults who have previously completely responded or partially responded to other chemotherapy treatments.

It is also used to treat certain types of cancer in people with specific gene (BRCA) changes who have received treatment with at least two other chemotherapy treatments. It is also indicated as maintenance therapy immediately after chemotherapy which has caused the tumor to shrink.

Rucaparib Dosage available

It is an orally available antineoplastic drug. The medicine is available as 200mg, 250mg, and 300mg tablets. Your doctor will decide the dose and duration of Rucaparib based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

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News/Updates

References

  1. Rubraca 250mg film-coated tablets – Summary of Product Characteristics (SmPC) – (emc). www.medicines.org.uk. [revised on 2022] [cited 2023 Apr 11]. Available from: https://www.medicines.org.uk/emc/product/10027/smpc
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION – Rucaparib. [revised on 2018] [cited 2023 Apr 11]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/209115s003lbl.pdf
  3. Shirley M. Rucaparib: A Review in Ovarian Cancer. Targeted Oncology. [2019 Apr 1] [cited 2022 Oct 15];14(2):237–46. Available from: https://pubmed.ncbi.nlm.nih.gov/30830551/
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Frequently Asked Questions

South Delhi Pharma is a consultancy company which facilitates patients, hospitals, clinicians and researchers in accessing products which are not available or approved in their home country. IPN also helps companies in designing and implementing PAP (Patient Assistance Plan) or Patient Centric Programs, CROs in accessing products for clinical trials. More Details

South Delhi Pharma 60/4, Yusaf Sarai, Near Indian Oil Corp., New Delhi – 110 016 (India) Email: [email protected]

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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