New Delhi, India – 110 016

Humimab HC (Adalimumab) Injection

Generic brands for Adalimumab Injection  Available in India

Brand Name Humimab HC
Generic Name Adalimumab
Strength 40mg
Manufacturer Sun Pharmaceutical Industries Ltd.

 

 

Description

Description

This page contains brief details about the drug adalimumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Adalimumab is a monoclonal antibody (protein which attaches to a specific target) which was approved for its medical use on 31st December 2002.

Mechanism of Action of Adalimumab

Adalimumab Injection is a biological agent that acts as targeted drug therapy to treat various inflammatory conditions. Adalimumab specifically targets and binds to the tnf Alpha. tnf Alpha a protein that is present in high concentrations in inflammatory diseases. adalimumab blocks the interaction of this protein with its receptors and eventually lower the inflammation.

Uses of Adalimumab

Adalimumab Injection has been developed to treat various inflammatory conditions like rheumatoid arthritis, polyarticular juvenile idiopathic arthritis, enthesitis-related arthritis, ankylosing spondylitis, axial spondylarthritis without evidence of ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, hidradenitis suppurativa, Crohn’s disease, ulcerative colitis and non-infective uveitis.

Adalimumab Dosage available

For adults with rheumatoid arthritis, psoriatic arthritis and ankylosing Spondylitis, the recommended dose is 40mg every other week. for children with Arthritis of unknown origin, the recommended dose is 10mg every other week for body weight less than 15 kg, 20mg every other week for body weight less than 30kg and 40mg every other week for body weight above 30kg.

For adults with inflammatory bowel disease like crohn’s disease and ulcerative colitis, the recommended dose is 160 MG on day 1, 80mg on 15th day and 40mg every other week starting on day 29. for children body weight less than 40 kg, the recommended dose is 80mg on first day, 40mg on day 15 and 20mg every other week starting on 29th day.

In case of plaque psoriasis and adult uveitis, initial dose is 80 mg followed by 40 mg every other week after initial dose. adalimumab is available as single dose prefilled pen (80mg/0.8ml, 40mg/0.8ml, 40mg/0.4ml) single dose prefilled glass syringe (80mg/0.8ml, 40mg/0.8ml, 40mg/0.4ml, 20mg/0.4ml, 20mg/0.2ml, 10mg/0.2ml, 10mg/0.1ml) and single dose glass vial (40mg/0.8ml).

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News/Updates

References

  1. AbbVie Ltd, Electronic Medicines Compendium (EMC), [Revised on Apr 2021] [Accessed on 12th Aug 2022], https://www.medicines.org.uk/emc/files/pil.7986.pdf
  2. AbbVie Ltd., U.S. Food and Drug Administration, [Revised on Feb 2021] [Accessed on 12th Aug 2022], https://www.rxabbvie.com/pdf/humira.pdf
    1. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Frequently Asked Questions

South Delhi Pharma is a consultancy company which facilitates patients, hospitals, clinicians and researchers in accessing products which are not available or approved in their home country. IPN also helps companies in designing and implementing PAP (Patient Assistance Plan) or Patient Centric Programs, CROs in accessing products for clinical trials. More Details

South Delhi Pharma 60/4, Yusaf Sarai, Near Indian Oil Corp., New Delhi – 110 016 (India) Email: [email protected]

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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