New Delhi, India – 110 016

Granicip (Granisetron) available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Granicip (Granisetron) Injection

Generic brands for Granisetron Injection Available in India

Brand Name Granicip
Generic Name Granisetron
Strength 3mg
Manufacturer Cipla Ltd

Description

Description

This page contains brief details about the drug granisetron, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Granisetron is an antiemetic drug that belongs to the class 5-HT 3 receptor antagonists and is effective against nausea and vomiting.  It was approved by the FDA on  25 July 1

Mechanism of Action of Granisetron

Granisetron is a potent, selective antagonist of 5-HT3 receptors. The antiemetic (effective against vomiting and nausea) activity of the drug is brought about through the inhibition of 5-HT3 receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HT3 receptors, in turn, blocks the substance serotonin, a natural substance in the body that causes nausea and vomiting.

Uses of Granisetron

Granisetron is indicated to prevent nausea and vomiting associated with initial and repeated courses of emetogenic (a substance that causes vomiting) chemotherapy and radiation therapy. It is also used to treat and prevent nausea and vomiting in adults that may occur after surgery.

Granisetron Dosage available

Granisetron is a prescription generic drug available as an injectable solution, extended-release subcutaneous injection, transdermal patch, tablet, and oral solution. The oral dose is given 1 hour before chemotherapy, followed by 12 hours after chemotherapy to prevent chemotherapy-induced nausea and vomiting. The recommended injection dose is 10 mcg/kg intravenously 30 minutes before chemotherapy. Your doctor will decide the dose, frequency, and dosage based on the severity of the condition. To prevent radiation-induced nausea and vomiting, the recommended dose is given orally 1 hour before radiation therapy. To prevent postoperative nausea and vomiting, the recommended dose is given intravenously before induction of anesthesia. To treat postoperative nausea and vomiting, the recommended dose is given intravenously.

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References

  1. HIGHLIGHTS OF PRESCRIBING INFORMATION. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020239s021,020305s014,021238s007lbl.pdf (Accessed on 21 December 2022)
  2. DailyMed – SUSTOL- granisetron injection. dailymed.nlm.nih.gov. Accessed December 22, 2022. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f7c7ffdd-8270-4030-bc1e-a1cb28a6de56&audience=consumer#section-5
  3. Granisetron: MedlinePlus Drug Information. medlineplus.gov. Accessed December 22, 2022. https://medlineplus.gov/druginfo/meds/a601211.html
  4. Tripathi KD. Essentials of Medical Pharmacology. Jaypee Brothers Medical Publishers; 2019: 716-717. Accessed December 21, 2022. file:///C:/Users/BIS/Downloads/Essentials%20of%20Medical%20Pharmacology%20(%20PDFDrive%20).pdf
  5. Minami M. Granisetron: is there a dose-response effect on nausea and vomiting? Cancer Chemother Pharmacol. 2003 Aug;52(2):89-98. doi: 10.1007/s00280-003-0652-6. Epub 2003 May 29. PMID: 12783208.
  6. Granisetron: Package Insert / Prescribing Information. Drugs.com. Published February 1, 2022. Accessed December 22, 2022. https://www.drugs.com/pro/granisetron.html
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Frequently Asked Questions

South Delhi Pharma is a consultancy company which facilitates patients, hospitals, clinicians and researchers in accessing products which are not available or approved in their home country. IPN also helps companies in designing and implementing PAP (Patient Assistance Plan) or Patient Centric Programs, CROs in accessing products for clinical trials. More Details

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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