New Delhi, India – 110 016

Crizalk (Crizotinib) Capsule

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Generic brands for Crizotinib Capsule Available in India

Brand Name Crizalk
Generic Name Crizotinib
Strength 200mg, 250mg
Manufacturer Pfizer Ltd

 

CRIZALK 200MG TAB. 1X60 85000 107189.96
CRIZALK 250 MG BOT (60 CAP) 1X60 92000 113709.17

Original price was: ₹107,189.96.Current price is: ₹85,000.00.

Description

Description

This page contains brief details about the drug crizotinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

CRIZALK 200MG TAB. 1X60 85000 107189.96
CRIZALK 250 MG BOT (60 CAP) 1X60 92000 113709.17

Date of Approval

The U.S. FDA-approved Crizotinib to treat people with ALK-positive NSCLC in the year of 2011.

Mechanism of Action of Crizotinib

Crizotinib Capsule is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a tyrosine kinase inhibitor. Anaplastic lymphoma kinase and ROS1 are two prominent genes that result in non-small cell lung cancer by undergoing mutation. Crizotinib acts by inhibiting these genes and stops the growth and development of cancer cells by shrinking them.

Uses of Crizotinib

Crizotinib capsule is indicated to treat the advanced stage of lung cancer as an initial treatment and is also recommended when other anticancer treatments did not work. It is prescribed to treat ALK-positive non-small cell lung cancer (NSCLC)

Crizotinib Dosage available

Crizotinib is available in 200mg and 250mg capsules. The recommended dose is 250mg twice daily, preferably one capsule each in the morning and evening. It is advisable to take this medicine at the same time each day with or without food. Swallow the capsule and do not crush, open, or dissolve them.

Additional information

Packing

1X60

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News/Updates

References

  1. Monarch Pharmaceuticals, US Food and Drug Administration, [ Revised on Oct 2006] [ Accessed on 13th June 2023],  https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050108s026lbl.pdf
  2. Millmount healthcare LTD., Electronic medicines compendium (emc), [ Revised on May 2022] [ Accessed on 13th June 2023], https://www.medicines.org.uk/emc/files/pil.1094.pdf
  3. Koomanachai P, Tiengrim S, Kiratisin P, Thamlikitkul V. Efficacy and safety of colistin (colistimethate sodium) for therapy of infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii in Siriraj Hospital, Bangkok, Thailand. Int J Infect Dis. 2007 Sep;11(5):402-6. doi: 10.1016/j.ijid.2006.09.011. Epub 2007 Feb 8. PMID: 17291803.
Ordering Information:

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