New Delhi, India – 110 016

Cyramza (Ramucirumab) Injection

Generic brands for Ramucirumab Injection Available in India

Brand Name Cyramza
Generic Name Ramucirumab
Strength 100mg 500mg
Manufacturer Eli Lilly And Company Ind

 

Description

Description

This page contains brief details about the drug ramucirumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Ramucirumab is an anticancer medication containing the active ingredient Ramucirumab. It is a monoclonal antibody drug. Cancer is a condition in which cells multiply uncontrolled and abnormally. This medication treats advanced stomach, colon, rectum, lungs, and liver cancers. It may be given alone or in combination with other anticancer medications to treat various types of cancer. The benefits of Ramucirumab are that it can help to slow down the growth and spread of cancer cells in various types of cancer. Studies have shown that this medication can improve survival rates and increase the time until cancer progresses to the advanced stage.

Ramucirumab was approved by the United States Food and Drug Administration (FDA) in April 2014 for the treatment of advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma, as well as for the treatment of metastatic non-small cell lung cancer (NSCLC) in combination with other anticancer drug.

Mechanism of Action of Ramucirumab

It works by targeting and inhibiting the action of a protein called vascular endothelial growth factor receptor 2 (VEGFR2), which plays a key role in the growth and development of blood vessels that feed tumors. By blocking VEGFR2, ramucirumab helps to prevent the growth and spread of cancer cells.

Uses of Ramucirumab

Ramucirumab is used to treat several types of cancer, including advanced gastric cancer or gastroesophageal junction adenocarcinoma, non-small cell lung cancer, hepatocellular carcinoma, and colorectal cancer.

Ramucirumab Dosage available

A healthcare professional administers Ramucirumab through intravenous injection in a hospital or clinic setting. It is not intended for self-administration. The recommended dosage and frequency depends on the type and stage of the cancer being treated, the individual patient’s medical history, and overall health status. The drug is usually administered with chemotherapy or as a standalone treatment.

If you miss a scheduled dose, contact your healthcare provider as soon as possible to discuss the best course of action. Sometimes, your healthcare provider may recommend that you receive the missed dose as soon as possible and then resume the regular dosing schedule. However, this will depend on several factors, such as how long it has been since your last dose, overall health status, and cancer stage. It is important not to double the dose to make up for a missed dose, as this can increase the risk of side effects.

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News/Updates

References

  1. Genzyme Corporation, U.S. Food & Drug Administration [Revised on Dec 2017] [Accessed on 13th Apr 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/022311s018lbl.pdf
  2. Seacross Pharmaceuticals Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 20th April 2023],  Plerixafor Seacross 20 mg/ml solution for injection – Patient Information Leaflet (PIL) – (emc) (medicines.org.uk)
  3. James L. Zehnder, Agents Used in Cytopenias; Hematopoietic Growth Factors, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 591- 607.

Frequently Asked Questions

South Delhi Pharma is a consultancy company which facilitates patients, hospitals, clinicians and researchers in accessing products which are not available or approved in their home country. IPN also helps companies in designing and implementing PAP (Patient Assistance Plan) or Patient Centric Programs, CROs in accessing products for clinical trials. More Details

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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