New Delhi, India – 110 016

Carfilnat (Carfilzomib) Injection available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Carfilnat (Carfilzomib) Injection

Generic brands for Carfilzomib Injection Available in India

Brand Name Carfilnat
Generic Name Carfilzomib
Strength 10mg, 30mg, 60mg
Manufacturer Natco Pharma Ltd

Description

Description

This page contains brief details about the drug carfilzomib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Carfilzomib is an anticancer medication containing the active constituent carfilzomib. It is used to treat a type of cancer called multiple myeloma. Multiple myeloma is a cancer of a white blood cell called the plasma cell. These cells grow uncontrolled and accumulate in the bone marrow, damaging the bones and kidneys. The treatment with this medication reduces symptoms of multiple myelomas, such as bone pain, fatigue, and anemia, improving a patient’s quality of life.

Carfilzomib was approved by the FDA on July 20, 2012, as a treatment for patients with multiple myeloma who have not responded to at least two prior therapies or whose disease has progressed within 60 days of completion of the last therapy. It is often used in combination with other medications.

Mechanism of Action of Carfilzomib

Carfilzomib is a proteasome inhibitor, which means it works by blocking the action of proteasomes, the enzymes responsible for breaking down proteins in cells. By blocking proteasomes, this medication can prevent the growth and survival of cancer cells, ultimately leading to the death of cancer cells. This can slow or stop the progression of multiple myeloma and may improve survival rates for some patients.

Uses of Carfilzomib

Carfilzomib is a medication used in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow.

Carfilzomib Dosage available

Carfilzomib is typically administered as an intravenous (IV) injection by a healthcare provider. The exact dosing and frequency of administration will depend on the specific condition being treated and other individual factors, such as the patient’s age, weight, and overall health. If a dose is missed, it’s important to contact your healthcare provider as soon as possible. Suppose the missed dose is discovered within a few hours of the scheduled time. In that case, your healthcare provider may recommend administering the missed dose as soon as possible while maintaining the usual interval between doses. However, if more than a few hours have passed since the missed dose, your healthcare provider may recommend skipping the missed dose and resuming the regular dosing schedule at the next scheduled time. Avoid double-up on doses to make up for a missed one.

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News/Updates

References

  1. Amgen Limited, Electronic medicines compendium (EMC), [Revised on August 2021] [ Accessed on 13th April 2023], https://www.medicines.org.uk/emc/files/pil.5061.pdf
  2. Onyx Pharmaceuticals, Inc, US Food and Drug Administration, [Revised on Feb 2019] [ Accessed on 13th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/202714s025lbl.pdf
  3. Anderson KC, Munshi NC. Hematologic Malignancies: Multiple Myeloma and Related Plasma Cell Disorders. New York: Springer; 2019.
  4. Kimberly Redic; Carfilzomib: A novel agent for multiple myeloma; The Journal of Pharmacy and Pharmacology, [ Revised on Aug 2013], [Accessed on 13th April 2023] https://pubmed.ncbi.nlm.nih.gov/23837578/
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Frequently Asked Questions

South Delhi Pharma is a consultancy company which facilitates patients, hospitals, clinicians and researchers in accessing products which are not available or approved in their home country. IPN also helps companies in designing and implementing PAP (Patient Assistance Plan) or Patient Centric Programs, CROs in accessing products for clinical trials. More Details

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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