New Delhi, India – 110 016

Sutib (Sunitinib) available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Sutib (Sunitinib) Capsule

Generic brands for Sunitinib Capsule Available in India

Brand Name Sutib
Generic Name Sunitinib
Strength 12.5mg,25mg, 50mg
Manufacturer Glenmark Pharmaceuticals

 

Description

Description

This page contains brief details about the drug sunitinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Sunitinib consist of the active ingredient Sunitinib. It is classified as a tyrosine kinase inhibitor, which means that it works by blocking certain enzymes called tyrosine kinases that are involved in the growth and spread of cancer cells. This medication is used to treat gastrointestinal stromal tumors (GIST), rare cancer that can start anywhere in the gastrointestinal tract. This medication is also used to treat advanced kidney cancer, and pancreatic cancer called pancreatic neuroendocrine tumors (PNET). Cancer is a disorder in which abnormal cells grow in an uncontrolled manner.  It is not recommended for people under 18.

Sunitinib was approved by the U.S. Food and Drug Administration (FDA) on January 26, 2006, for the treatment of gastrointestinal stromal tumor (GIST) after disease progression or intolerance to other medication. Since then, sunitinib has also received FDA approval for other cancer treatments also. Before taking this medication, it is important to discuss with the physician if you have blood conditions, heart problems, liver disorders, kidney problems, skin disorders, diabetes, seizures, or thyroid disorders. Also, inform if you have recently had surgery or are about to have surgery.

Mechanism of Action of Sunitinib

Sunitinib works by including slowing down or stopping the growth and spread of cancer cells in the body, thereby reducing the size and number of tumors. This medication inhibits the activity of specific proteins known as tyrosine kinases, which are involved in the signaling pathways that control cell growth and division. It can help prevent cancer cells from growing and spreading by blocking these pathways.

Uses of Sunitinib

Sunitinib is a targeted therapy medicine used to treat advanced or metastatic kidney cancer, gastrointestinal stromal tumors (GIST), and certain types of pancreatic neuroendocrine tumors (PNET). It also uses in the treatment of medullary thyroid cancer.

Sunitinib Dosage available

Sunitinib is taken orally, in the form of capsules, with a glass of water. The capsules should be swallowed whole and not crushed, chewed, or opened. The recommended dose may vary depending on the type of cancer being treated, the patient’s age and weight, and other factors. This medication is usually taken once a day, with or without food, at around the same time each day. If you miss a dose then do not double the dose to compensate for the missed dose.

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News/Updates

References

  1. Pfizer, U.S Drug and food safety administration (FDA), [Revised on Dec 2018], [Accessed on 5th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021938s035lbl.pdf
  2. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
  3. Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo, Tyrosine Kinase Inhibitors, [Revised on 21st Jan 2021] [Accessed on 5th April 2023],
    https://www.ncbi.nlm.nih.gov/books/NBK563322/
  4. Pfizer, Electronic Medicines Compendium (EMC) [Revised on Mar 2021] [Accessed on 5th April 2023],  https://www.medicines.org.uk/emc/files/pil.7966.pdf
  5. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936

 

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There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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