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Biomab Egfr (Nimotuzumab) Injection

Generic brands for Nimotuzumab Injection Available in India

Brand Name Biomab Egfr
Generic Name Nimotuzumab
Strength
Manufacturer Biocon Ltd

 

Description

Description

This page contains brief details about the drug nimotuzumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Nimotuzumab consists of the active Nimotuzumab. It is a monoclonal antibody used in cancer treatment.  It has been approved for the treatment of head and neck cancer, as well as for certain types of brain cancer. This medication is typically used with other cancer treatments, such as chemotherapy and radiation therapy.

There are no absolute contraindications to Nimotuzumab, but there are some precautions and potential contraindications to consider. For example, patients with a history of severe allergic reactions or hypersensitivity to it or its components should not receive the medication. Additionally, patients with certain medical conditions, such as severe liver or kidney disease, may need to be monitored closely or have their dosages adjusted.

Mechanism of Action of Nimotuzumab

Nimotuzumab is primarily focused on its ability to target and bind to the epidermal growth factor receptor (EGFR) found on many cancer cells. By doing so, it can block the growth and spread of cancer cells, ultimately leading to improved outcomes for cancer patients. One of the advantages of this medication is its targeted therapy approach, which allows it to target cancer cells while minimizing damage to healthy cells specifically. This can help to reduce side effects and improve the overall quality of life for cancer patients undergoing treatment.

Uses of Nimotuzumab

Nimotuzumab is used in the treatment of several types of cancer, including head and neck cancer and certain types of brain cancer, such as glioma and glioblastoma. It is often combined with other cancer treatments, such as chemotherapy and radiation therapy, to improve overall and disease-free outcomes.

Nimotuzumab Dosage available

Nimotuzumab is an injectable medication that a healthcare professional administers. It is typically given as an intravenous injection. The dose and frequency will depend on the type of cancer being treated, the patient’s overall health, and other medications the patient may be taking.  If you miss a dose, contact your healthcare provider as soon as possible. Your healthcare provider may recommend rescheduling your next dose or adjusting your dosing schedule. Do not double the dose to make a missed dose.

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News/Updates

References

  1. Goodman and Gilman’s, The Pharmacological Basis of Therapeutics,12th edition, 2018, 1688-1693
  2. Hospira UK Ltd, Electronic Medicines Compendium (EMC), [Revised on 30th March 2023], [Accessed on 31st March 2023], https://www.medicines.org.uk/emc/files/pil.6455.pdf
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