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Ramiven (Abemaciclib) Tablets

Generic brands for Abacavir,Dolutegravir,Lamivudine Injection  Available in India

Brand Name Ramiven
Generic Name Abemaciclib
Strength
Manufacturer Eli Lilly And Company India Pvt Ltd

Description

Description

This page contains brief details about the drug abemaciclib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Abemaciclib is an anticancer medication containing the active ingredient Abemaciclib.  It is a prescription medication that belongs to a class of drugs known as cyclin-dependent kinase (CDK) inhibitors. It is used to treat certain types of cancer.

Mechanism of Action of Abemaciclib

Abemaciclib works by blocking the activity of CDK4 and CDK6 enzymes, which are involved in cell division and growth. By inhibiting these enzymes, it slows down or stops the growth of cancer cells.

Uses of Abemaciclib

Abemaciclib is a single-agent treatment for advanced or metastatic breast cancer that has progressed despite other treatments, or in combination with other drugs as a first-line treatment. In combination with other drugs, it is also used in the treatment of advanced or metastatic breast cancer, non-small cell lung cancer, endometrial cancer and pediatric patients with neuroblastoma.

Abemaciclib Dosage available

Abemaciclib is usually taken orally, with or without food. The tablets should be swallowed whole with a glass of water and not crushed, chewed or broken. The dosage and frequency will depend on various factors, including the patient’s age, weight, overall health, and the type and stage of cancer being treated. It’s important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. If a dose is missed, it should be taken as soon as possible unless it’s within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. It is important not to take a double dose to make up for a missed dose.

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References
Eli Lilly Nederland BV, Electronic medicines compendium (emc), [Revised on May 2022] [ Accessed on 29 March 2023], https://www.medicines.org.uk/emc/files/pil.11046.pdf
Lilly USA, US Food and Drug Administration, [Revised on October 2021] [Accessed on 29 March2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/208716s006s007s008lbl.pdf
DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology Authors,11th Edition, 2018, 1006-1022
Bruce A. Chabner, Dan L. Longo, Cancer Chemotherapy and Biotherapy: Principles and Practice, Edition: 6th, 2019, 501-502

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