New Delhi, India – 110 016

Colstim (Filgrastim) Injection available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Colstim (Filgrastim) Injection

Generic brands for Filgrastim Injection Available in India

Brand Name Colstim
Generic Name Filgrastim
Strength 300mcg
Manufacturer Zydus Cadila

Description

Description

This page contains brief details about the drug filgrastim, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Filgrastim is a granulocyte colony-stimulating factor which was approved for its medical use in 1991 by FDA.

Mechanism of Action of Filgrastim

Filgrastim Injection is a granulocyte colony-stimulating factor that belongs to the group of medications called cytokines. Growth factors are proteins naturally occurring in the body. Filgrastim works by stimulating the bone marrow to produce more white blood cells to fight off infections.

Uses of Filgrastim

Filgrastim decreases the risk of developing febrile neutropenia (occurrence of fever or infection associated with low WBC count) and reduces the duration of neutropenia (low white blood cell count) in people who have non-myeloid cancer and are receiving chemotherapy drugs. It is also used to increase the number of WBC and decrease the length of time of fever in people with acute myeloid leukemia.

It is also used in people undergoing bone marrow transplants and in people with severe chronic neutropenia (low number of neutrophils in the blood). Filgrastim is also used to prepare the blood for leukapheresis (a treatment in which certain blood cells are removed from the blood). It is also indicated to increase the chance of survival in people exposed to harmful amounts of radiation, which can cause severe damage to the bone marrow. Other uses include in patients with advanced HIV infection, which will help to reduce the risk of infections.

Filgrastim Dosage available

Filgrastim is available as a prefilled syringe and solution for injection, intended for subcutaneous or intravenous administration. It is available in a dose 300mcg. The dosing depends on your body weight and severity of illness. your healthcare professional will determine the dose, route of administration, frequency, and duration of treatment based on your disease condition and other factors.

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References

  1. Amgen Europe Ltd., Electronic Medicines Compendium (EMC), [Revised on Jul 2022] [Accessed on 28th Oct 2022], https://www.medicines.org.uk/emc/files/pil.3000.pdf
  2. James L. Zehnder, Agents Used in Cytopenias; Hematopoietic Growth Factors, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 591-607.
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There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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