New Delhi, India – 110 016

Neolistim (Colistimethate Sodium) Injection

Generic brands for Colistimethate Sodium Injection Available in India

Brand Name Neolistim
Generic Name Colistimethate Sodium
Strength 1MIU, 3MIU, 4.5MIU
Manufacturer Neon Laboratories Ltd

Description

Description

This page contains brief details about the drug colistimethate sodium, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Colistimethate Sodium is a polymixin antibiotic agent. Initially, Colistin was discovered in 1947, and FDA approved Colistimethate sodium was approved for medical use in 1970

Mechanism of Action of Colistimethate Sodium

Colistimethate sodium, a polypeptide antibiotic, penetrates and disrupts the bacterial cell membrane of susceptible strains of aerobic gram-negative bacteria. It works by killing bacteria

Uses of Colistimethate Sodium

Colistimethate Sodium is used to treat certain types of infections caused by bacteria. This medicine is commonly used when other antibiotics are not suitable. It is sometimes given as an inhalation to treat chronic chest infections in patients with cystic fibrosis. This medicine is used when these infections are caused by specific bacteria called Pseudomonas aeruginosa.

Colistimethate Sodium Dosage available

A doctor or nurse in a hospital or clinic setting will give it to you. Depending on the reason, the drug may be given by fast or slow injection into a vein. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.

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News/Updates

References

  1. Monarch Pharmaceuticals, US Food and Drug Administration, [ Revised on Oct 2006] [ Accessed on 13th June 2023],  https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050108s026lbl.pdf
  2. Millmount healthcare LTD., Electronic medicines compendium (emc), [ Revised on May 2022] [ Accessed on 13th June 2023], https://www.medicines.org.uk/emc/files/pil.1094.pdf
  3. Koomanachai P, Tiengrim S, Kiratisin P, Thamlikitkul V. Efficacy and safety of colistin (colistimethate sodium) for therapy of infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii in Siriraj Hospital, Bangkok, Thailand. Int J Infect Dis. 2007 Sep;11(5):402-6. doi: 10.1016/j.ijid.2006.09.011. Epub 2007 Feb 8. PMID: 17291803.
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