New Delhi, India – 110 016

Candipoz GR (Posaconazole) Tablet available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Candipoz GR (Posaconazole) Tablet

Generic brands for Posaconazole Tablet Available in India

Brand Name Candipoz GR
Generic Name Posaconazole
Strength 100mg, 300mg
Manufacturer Glenmark Pharmaceuticals

Description

Description

This page contains brief details about the drug posaconazole, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Posaconazole is a group of medicines called Azole antifungals. The U.S. FDA officially approved Posaconazole for its medical use in 2006.

Mechanism of Action of Posaconazole

Posaconazole inhibits ergosterol synthesis by binding and inhibiting the lanosterol-14alpha-demethylase enzyme, which is found in almost all fungi and is a key component of the fungal cell membrane. It stops the activity of the organisms responsible for fungus infections.

Uses of Posaconazole

Posaconazole is used to treat fungal infections, oropharyngeal candidiasis (OPC), and  Prophylaxis of invasive aspergillus and candida infections in severely immunocompromised patients.

Posaconazole Dosage available

Posaconazole is available as an injection, delayed-release tablet, syrup or oral suspension. The recommended dose of Posaconazole tablet is 300 mg twice daily and must be taken with food. Avoid crushing, chewing, or breaking the tablets; swallow them whole. Posaconazole injection is usually given over 30 to 90 minutes in your vein. Take each oral suspension dose within 20 minutes after a full meal. A measured dosing spoon comes with your oral suspension and is marked for  2.5 ml and 5 ml doses. Follow your doctor’s instructions attentively and continue to take it at the dose and time suggested by your doctor. It may worsen your symptoms, so don’t stop taking it without first talking to your doctor.

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News/Updates

References

1. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018

References

  1. Merck Sharp & Dohme (UK) Limited, Electronic Medicines Compendium (EMC), [Revised on Oct 2021] [Accessed on 18th Aug 2022], https://www.medicines.org.uk/emc/files/pil.5388.pdf
  2. Merck Sharp & Dohme Corporation, U.S. Food and Drug Administration, [Revised on 2015] [Accessed on 18th Aug 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022003s018s020,0205053s002s004,0205596s001s003lbl.pdf
  3. L. Chen et al., Pharmacokinetics and Pharmacodynamics of Posaconazole, Drugs, 2020, 80:671–695, https://link.springer.com/content/pdf/10.1007/s40265-020-01306-y.pdf

, 948-976.

2. Novartis Pharmaceuticals, US Food & Drug Administration (FDA), [Revised on Dec 2021] [Accessed on 19th Sep 2022], https://www.novartis.com/us-en/sites/novartis_us/files/votrient.pdf

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South Delhi Pharma is a consultancy company which facilitates patients, hospitals, clinicians and researchers in accessing products which are not available or approved in their home country. IPN also helps companies in designing and implementing PAP (Patient Assistance Plan) or Patient Centric Programs, CROs in accessing products for clinical trials. More Details

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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