New Delhi, India – 110 016

Azaplast (Azacitidine) available Delhi, Mumbai, Madras, Hyderabad, Bangalore India

Azaplast (Azacitidine) Injection

Generic brands for Azacitidine Injection  Available in India

Brand Name Azaplast
Generic Name Azacitidine
Strength 100mg, 200mg
Manufacturer Rpg Life Sciences Ltd

Description

Description

This page contains brief details about the drug azacitidine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Azacitidine is an anticancer medication which was approved for its medical use on 19th May 2004.

Mechanism of Action of Azacitidine

Azacitidine is a cytotoxic anticancer medication belonging to the category of medications called antimetabolites. It is also called as the demethylating or hypomethylating agent. It enters the DNA and forms a covalent bond with the DNA methyltransferase and induces programmed cell death of tumour cells.

Uses of Azacitidine

Azacitidine is a prescription medicine indicated to treat adults with acute myeloid leukemia and myelodysplastic syndrome and peadiatric patients older than one month newly diagnosed with Juvenile Myelomonocytic Leukemia (JMML).

Azacitidine Dosage available

Azacitidine is available in form of tablets in the doses 200mg and 300mg and as lyophilized powder for injection in the doses 100mg and 150mg. the injection is intended for administration through subcutaneous and intravenous route only.

Take 1 Azacitidine Tablet with or without food everyday from day 1 to day 14 of each 28-day cycle. Azacitidine Injection will be administered by your oncologist through subcutaneous or intravenous route and the number of cycles and duration of treatment depends on the type of cancer.

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News/Updates

References

  1. Bristol Myers Squibb, [Revised on May 2021] [Accessed on 12th Oct 2022], https://packageinserts.bms.com/pi/pi_onureg.pdf
  2. Bristol Myers Squibb, [Revised on Sep 2022] [Accessed on 12th Oct 2022], https://packageinserts.bms.com/pi/pi_vidaza.pdf
  3. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Goodman & Gilman’s Pharmacological Basis of Therapeutics, Cytotoxic Drugs, 13th Edition, 2018, 1167-1201.
  4. Čemažar L, Podgornik H, Šimec NG, Zver S. Successful long-term treatment with azacitidine in patient with chronic myelomonocytic leukemia. Hematol Rep. 2020 Dec 2;12(3):8537, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731662/pdf/hr-12-3-8537.pdf
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Frequently Asked Questions

South Delhi Pharma is a consultancy company which facilitates patients, hospitals, clinicians and researchers in accessing products which are not available or approved in their home country. IPN also helps companies in designing and implementing PAP (Patient Assistance Plan) or Patient Centric Programs, CROs in accessing products for clinical trials. More Details

South Delhi Pharma 60/4, Yusaf Sarai, Near Indian Oil Corp., New Delhi – 110 016 (India) Email: [email protected]

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Medicines once shipped will not be taken back. We will assist you with the Export Invoice and tracking details of your order. International orders might be subject to import taxes/duties. For information, please contact your local customs authority. Any such taxes are the responsibility of the parcel recipient and are not paid by us.

There are some medicines which have been approved recently in USA or Europe but not yet approved in India or any other countries are not permitted to be imported or marketed commercially. However, they may be required for the treatment of patients to save their lives who have exhausted all other available treatment options in their country. Named – Patient Program is to facilitate import of such medicines for personal use. There is a provision under the Indian Drugs and Cosmetics Rules, 1945, that permits the patient to import these medicine in small quantity. Similar regulatory provision also exist in other countries. We assist patient in preparing legal documents for import and connecting them with authorized suppliers in USA and Europe to secure genuine products.

A generic drug is a drug defined as “a drug product that is comparable to a brand/reference listed drug product in dosage form, strength, quality and performance characteristics, and intended use”. There are Indian companies which manufacture and market these generic medicines after getting approval from Regulatory Authority of the country. These generic medicines contain the same active ingredients as the original formulation and are identical or within an acceptable bioequivalent range to the Innovator drug counterpart with respect to pharmacokinetic and pharmaco-dynamic properties. By extension, therefore, generics are considered identical in dose, strength, route of administration, safety, efficacy, and intended use. They are labeled with the name of the manufacturer and the adopted name (nonproprietary name) of the drug. When generic products become available, the market competition often leads to substantially lower prices and thereby make is affordable for large number of needy patients.

It usually takes 8-9 working days after dispatch to reach medicine at outside India locations. Additional delays may occur due to heavy load on postal services and customs.

We advise to transfer money only through Interbank Transfer Modalities;

  • Online Net-banking for within India transfer.
  • International Wire Transfer (SWIFT) from outside India.
  • Cash on Delivery within India.

Cash on Delivery (COD) option is only available if the medicine is purchased and delivered in India. Preferred locations within India for COD facilities are within Municipal limits of New Delhi & NCR, Mumbai, Bangalore, Kolkata, Chennai & Hyderabad

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